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QUDeX-MS: hydrogen/deuterium exchange calculation for mass spectra with resolved isotopic fine structure
BACKGROUND: Hydrogen/deuterium exchange (HDX) coupled to mass spectrometry permits analysis of structure, dynamics, and molecular interactions of proteins. HDX mass spectrometry is confounded by deuterium exchange-associated peaks overlapping with peaks of heavy, natural abundance isotopes, such as...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274694/ https://www.ncbi.nlm.nih.gov/pubmed/25495703 http://dx.doi.org/10.1186/s12859-014-0403-1 |