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AMPD1: a novel therapeutic target for reversing insulin resistance

BACKGROUND: Insulin resistance is one of the hallmark manifestations of obesity and Type II diabetes and reversal of this pathogenic abnormality is an attractive target for new therapies for Type II diabetes. A recent report that metformin, a drug known to reverse insulin resistance, demonstrated in...

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Detalles Bibliográficos
Autores principales: Cheng, Jidong, Morisaki, Hiroko, Toyama, Keiko, Sugimoto, Naomi, Shintani, Takuya, Tandelilin, Andreas, Hirase, Tetsuaki, Holmes, Edward W, Morisaki, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274759/
https://www.ncbi.nlm.nih.gov/pubmed/25511531
http://dx.doi.org/10.1186/1472-6823-14-96