Compartmentalized Acyl-CoA Metabolism in Skeletal Muscle Regulates Systemic Glucose Homeostasis

The impaired capacity of skeletal muscle to switch between the oxidation of fatty acid (FA) and glucose is linked to disordered metabolic homeostasis. To understand how muscle FA oxidation affects systemic glucose, we studied mice with a skeletal muscle–specific deficiency of long-chain acyl-CoA syn...

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Detalles Bibliográficos
Autores principales: Li, Lei O., Grevengoed, Trisha J., Paul, David S., Ilkayeva, Olga, Koves, Timothy R., Pascual, Florencia, Newgard, Christopher B., Muoio, Deborah M., Coleman, Rosalind A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2015
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274800/
https://www.ncbi.nlm.nih.gov/pubmed/25071025
http://dx.doi.org/10.2337/db13-1070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274800/
https://www.ncbi.nlm.nih.gov/pubmed/25071025
http://dx.doi.org/10.2337/db13-1070

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