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Mineralocorticoid Receptor Blockade Improves Coronary Microvascular Function in Individuals With Type 2 Diabetes

Reduced coronary flow reserve (CFR), an indicator of coronary microvascular dysfunction, is seen in type 2 diabetes mellitus (T2DM) and predicts cardiac mortality. Since aldosterone plays a key role in vascular injury, the aim of this study was to determine whether mineralocorticoid receptor (MR) bl...

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Detalles Bibliográficos
Autores principales: Garg, Rajesh, Rao, Ajay D., Baimas-George, Maria, Hurwitz, Shelley, Foster, Courtney, Shah, Ravi V., Jerosch-Herold, Michael, Kwong, Raymond Y., Di Carli, Marcelo F., Adler, Gail K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274801/
https://www.ncbi.nlm.nih.gov/pubmed/25125488
http://dx.doi.org/10.2337/db14-0670