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Antidiabetic Activity of Benzopyrone Analogues in Nicotinamide-Streptozotocin Induced Type 2 Diabetes in Rats

Benzopyrones are proven antidiabetic drug candidate in diabetic drug discovery. In this view novel synthetic benzopyrone analogues were selected for testing in experimental diabetes. Type 2 diabetes (T2D) was induced in Wistar rats by streptozotocin (60 mg/kg, i.p.) followed by nicotinamide (120 mg/...

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Detalles Bibliográficos
Autores principales: Nayak, Yogendra, Hillemane, Venkatachalam, Daroji, Vijay Kumar, Jayashree, B. S., Unnikrishnan, M. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274851/
https://www.ncbi.nlm.nih.gov/pubmed/25548795
http://dx.doi.org/10.1155/2014/854267