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Comparative analysis of nucleotide translocation through protein nanopores using steered molecular dynamics and an adaptive biasing force

The translocation of nucleotide molecules across biological and synthetic nanopores has attracted attention as a next generation technique for sequencing DNA. Computer simulations have the ability to provide atomistic-level insight into important states and processes, delivering a means to develop a...

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Detalles Bibliográficos
Autores principales: Martin, Hugh S C, Jha, Shantenu, Coveney, Peter V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274958/
https://www.ncbi.nlm.nih.gov/pubmed/24403093
http://dx.doi.org/10.1002/jcc.23525