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Modeling the influence of short term depression in vesicle release and stochastic calcium channel gating on auditory nerve spontaneous firing statistics

We propose several modifications to an existing computational model of stochastic vesicle release in inner hair cell ribbon synapses, with the aim of producing simulated auditory nerve fiber spiking data that more closely matches empirical data. Specifically, we studied the inter-spike-interval (ISI...

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Detalles Bibliográficos
Autores principales: Moezzi, Bahar, Iannella, Nicolangelo, McDonnell, Mark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274967/
https://www.ncbi.nlm.nih.gov/pubmed/25566047
http://dx.doi.org/10.3389/fncom.2014.00163