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Transcriptional downregulation of agr expression in Staphylococcus aureus during growth in human serum can be overcome by constitutively active mutant forms of the sensor kinase AgrC

The temporal and cell density-dependent regulation of expression of virtually all the Staphylococcus aureus virulon is under the control of the agr (accessory gene regulatory) operon. The expression of the agr operon is subject to transcriptional regulation by the AgrA/C two-component response regul...

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Detalles Bibliográficos
Autores principales: James, Ellen H, Edwards, Andrew M, Wigneshweraraj, Sivaramesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274972/
https://www.ncbi.nlm.nih.gov/pubmed/24164684
http://dx.doi.org/10.1111/1574-6968.12309