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Elevated cerebrospinal fluid 5-hydroxyindoleacetic acid in macaques following early life stress and inverse association with hippocampal volume: preliminary implications for serotonin-related function in mood and anxiety disorders

Background: Early life stress (ELS) is cited as a risk for mood and anxiety disorders, potentially through altered serotonin neurotransmission. We examined the effects of ELS, utilizing the variable foraging demand (VFD) macaque model, on adolescent monoamine metabolites. We sought to replicate an i...

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Detalles Bibliográficos
Autores principales: Coplan, Jeremy D., Fulton, Sasha L., Reiner, Wade, Jackowski, Andrea, Panthangi, Venkatesh, Perera, Tarique D., Gorman, Jack M., Huang, Yung-yu, Tang, Cheuk Y., Hof, Patrick R., Kaffman, Arie, Dwork, Andrew J., Mathew, Sanjay J., Kaufman, Joan, Mann, J. John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274982/
https://www.ncbi.nlm.nih.gov/pubmed/25566007
http://dx.doi.org/10.3389/fnbeh.2014.00440