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A Practical Route to Substituted 7-Aminoindoles from Pyrrole-3-carboxaldehydes
[Image: see text] Among privileged structures, indoles occupy a central place in medicinal chemistry and alkaloid research. Here we report a flexible and efficient conversion of pyrrole-3-carboxaldehydes to substituted 7-amino-5-cyanoindoles. Phosphine addition to fumaronitrile proceeds with prototr...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275132/ https://www.ncbi.nlm.nih.gov/pubmed/25479249 http://dx.doi.org/10.1021/ol503078h |