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A Practical Route to Substituted 7-Aminoindoles from Pyrrole-3-carboxaldehydes

[Image: see text] Among privileged structures, indoles occupy a central place in medicinal chemistry and alkaloid research. Here we report a flexible and efficient conversion of pyrrole-3-carboxaldehydes to substituted 7-amino-5-cyanoindoles. Phosphine addition to fumaronitrile proceeds with prototr...

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Detalles Bibliográficos
Autores principales:	Outlaw, Victor K., Townsend, Craig A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275132/ https://www.ncbi.nlm.nih.gov/pubmed/25479249 http://dx.doi.org/10.1021/ol503078h

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