Radiolabeling of Poly(lactic-co-glycolic acid) (PLGA) Nanoparticles with Biotinylated F-18 Prosthetic Groups and Imaging of Their Delivery to the Brain with Positron Emission Tomography

[Image: see text] The avidin–biotin interaction permits rapid and nearly irreversible noncovalent linkage between biotinylated molecules and avidin-modified substrates. We designed a biotinylated radioligand intended for use in the detection of avidin-modified polymer nanoparticles in tissue with po...

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Detalles Bibliográficos
Autores principales: Sirianni, Rachael W., Zheng, Ming-Qiang, Patel, Toral R., Shafbauer, Thomas, Zhou, Jiangbing, Saltzman, W. Mark, Carson, Richard E., Huang, Yiyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275164/
https://www.ncbi.nlm.nih.gov/pubmed/25322194
http://dx.doi.org/10.1021/bc500315j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275164/
https://www.ncbi.nlm.nih.gov/pubmed/25322194
http://dx.doi.org/10.1021/bc500315j

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