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A Pharmaco-Metabonomic Study on Chronic Kidney Disease and Therapeutic Effect of Ergone by UPLC-QTOF/HDMS

Chronic kidney disease (CKD) is an important public health problem. Ergone has been proved to prevent the progression of CKD. UPLC-QTOF/HDMS was employed for metabolic profiling of adenine-induced CKD and to investigate the nephroprotective effects of ergone. Pharmacology parameters including blood...

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Detalles Bibliográficos
Autores principales: Zhao, Ying-Yong, Chen, Hua, Tian, Ting, Chen, Dan-Qian, Bai, Xu, Wei, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275224/
https://www.ncbi.nlm.nih.gov/pubmed/25535749
http://dx.doi.org/10.1371/journal.pone.0115467