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Sorting Nexin 6 Enhances Lamin A Synthesis and Incorporation into the Nuclear Envelope

Nuclear lamins are important structural and functional proteins in mammalian cells, but little is known about the mechanisms and cofactors that regulate their traffic into the nucleus. Here, we demonstrate that trafficking of lamin A, but not lamin B1, and its assembly into the nuclear envelope are...

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Detalles Bibliográficos
Autores principales: González-Granado, Jose M., Navarro-Puche, Ana, Molina-Sanchez, Pedro, Blanco-Berrocal, Marta, Viana, Rosa, de Mora, Jaime Font, Andrés, Vicente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275242/
https://www.ncbi.nlm.nih.gov/pubmed/25535984
http://dx.doi.org/10.1371/journal.pone.0115571