Implications of Targeted Genomic Disruption of β-Catenin in BxPC-3 Pancreatic Adenocarcinoma Cells

Pancreatic adenocarcinoma (PA) is among the most aggressive human tumors with an overall 5-year survival rate of <5% and available treatments are only minimal effective. WNT/β-catenin signaling has been identified as one of 12 core signaling pathways that are commonly mutated in PA. To obtain mor...

Descripción completa

Detalles Bibliográficos
Autores principales: Olsen, Petter Angell, Solberg, Nina Therese, Lund, Kaja, Vehus, Tore, Gelazauskaite, Monika, Wilson, Steven Ray, Krauss, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275244/
https://www.ncbi.nlm.nih.gov/pubmed/25536063
http://dx.doi.org/10.1371/journal.pone.0115496

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275244/
https://www.ncbi.nlm.nih.gov/pubmed/25536063
http://dx.doi.org/10.1371/journal.pone.0115496

Ejemplares similares