Cargando…

Implications of Targeted Genomic Disruption of β-Catenin in BxPC-3 Pancreatic Adenocarcinoma Cells

Pancreatic adenocarcinoma (PA) is among the most aggressive human tumors with an overall 5-year survival rate of <5% and available treatments are only minimal effective. WNT/β-catenin signaling has been identified as one of 12 core signaling pathways that are commonly mutated in PA. To obtain mor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Olsen, Petter Angell, Solberg, Nina Therese, Lund, Kaja, Vehus, Tore, Gelazauskaite, Monika, Wilson, Steven Ray, Krauss, Stefan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275244/ https://www.ncbi.nlm.nih.gov/pubmed/25536063 http://dx.doi.org/10.1371/journal.pone.0115496

Ejemplares similares

Expression profiling of wild type and β-catenin gene disrupted human BxPC-3 pancreatic adenocarcinoma cells
por: Olsen, Petter Angell, et al.
Publicado: (2015)

Antiproliferative effect of alpinetin in BxPC-3 pancreatic cancer cells
por: DU, JIAN, et al.
Publicado: (2012)

Antiproliferative effect of alpinetin in BxPC-3 pancreatic cancer cells
por: Du, Jian, et al.
Publicado: (2023)

Comparing the Effects of Intracellular and Extracellular Magnetic Hyperthermia on the Viability of BxPC-3 Cells
por: Hannon, Gary, et al.
Publicado: (2020)

Intracellular Distributing and Interferon-γ Secretion of Human Interleukin-18 in BxPC-3 Cells
por: Yang, Jin, et al.
Publicado: (2014)

Oridonin alters the expression profiles of MicroRNAs in BxPC-3 human pancreatic cancer cells
por: Gui, Zhifang, et al.
Publicado: (2015)

Proton Therapy, Magnetic Nanoparticles and Hyperthermia as Combined Treatment for Pancreatic BxPC3 Tumor Cells
por: Brero, Francesca, et al.
Publicado: (2023)

Effects of Metallic and Carbon-Based Nanomaterials on Human Pancreatic Cancer Cell Lines AsPC-1 and BxPC-3
por: Wójcik, Barbara, et al.
Publicado: (2021)

Enhanced tumor targeting of cRGD peptide-conjugated albumin nanoparticles in the BxPC-3 cell line
por: Yu, Xinzhe, et al.
Publicado: (2016)

Comparative analysis of Notch1 and Notch2 binding sites in the genome of BxPC3 pancreatic cancer cells
por: Liu, Hao, et al.
Publicado: (2017)

Cytotoxic effect of Efavirenz in BxPC-3 pancreatic cancer cells is based on oxidative stress and is synergistic with ionizing radiation
por: Hecht, Markus, et al.
Publicado: (2018)

Silencing NEDD9 by lentivirus-delivered shRNA inhibits the growth of BxPC-3 cells in vitro and in vivo
por: Wu, Tielong, et al.
Publicado: (2019)

Phenolic alkaloids from Menispermum dauricum inhibits BxPC-3 pancreatic cancer cells by blocking of Hedgehog signaling pathway
por: Zhou, Zhong-guang, et al.
Publicado: (2015)

Expression of Selected miRNAs in Normal and Cancer-Associated Fibroblasts and in BxPc3 and MIA PaCa-2 Cell Lines of Pancreatic Ductal Adenocarcinoma
por: Mandys, Václav, et al.
Publicado: (2023)

Inhibitory Effect of the HASPIN Inhibitor CHR-6494 on BxPC-3-Luc, A Luciferase-Expressing Pancreatic Cancer Cell Line
por: Tanaka, Hiromitsu, et al.
Publicado: (2022)

MS-5, a Naphthalene Derivative, Induces Apoptosis in Human Pancreatic Cancer BxPC-3 Cells by Modulating Reactive Oxygen Species
por: Giri, Suman, et al.
Publicado: (2023)

BxPC3 pancreatic cancer cells express a truncated Smad4 protein upon PI3K and mTOR inhibition
por: LEGENDRE, ONICA, et al.
Publicado: (2014)

BxPC-3-Derived Small Extracellular Vesicles Induce FOXP3+ Treg through ATM-AMPK-Sirtuins-Mediated FOXOs Nuclear Translocations
por: Shen, Tao, et al.
Publicado: (2020)

Salidroside ameliorated hypoxia‐induced tumorigenesis of BxPC‐3 cells via downregulating hypoxia‐inducible factor (HIF)‐1α and LOXL2
por: Chen, Xiaoping, et al.
Publicado: (2019)

The natural sulfoglycolipid derivative SQAP improves the therapeutic efficacy of tissue factor-targeted radioimmunotherapy in the stroma-rich pancreatic cancer model BxPC-3
por: Takakusagi, Yoichi, et al.
Publicado: (2021)

Dickkopf-related protein 3 alters aerobic glycolysis in pancreatic cancer BxPC-3 cells, promoting CD4(+) T-cell activation and function
por: Guo, Qingqu, et al.
Publicado: (2021)

5-FU resistant EMT-like pancreatic cancer cells are hypersensitive to photochemical internalization of the novel endoglin-targeting immunotoxin CD105-saporin
por: Lund, Kaja, et al.
Publicado: (2017)

Dihomo-γ-linolenic acid inhibits growth of xenograft tumors in mice bearing human pancreatic cancer cells (BxPC-3) transfected with delta-5-desaturase shRNA
por: Yang, Xiaoyu, et al.
Publicado: (2018)

MEK Inhibition Induces Canonical WNT Signaling through YAP in KRAS Mutated HCT-15 Cells, and a Cancer Preventive FOXO3/FOXM1 Ratio in Combination with TNKS Inhibition
por: Solberg, Nina Therese, et al.
Publicado: (2019)

Response gene to complement-32 enhances metastatic phenotype by mediating transforming growth factor beta-induced epithelial-mesenchymal transition in human pancreatic cancer cell line BxPC-3
por: Zhu, Liang, et al.
Publicado: (2012)

ASF-4-1 fibroblast-rich culture increases chemoresistance and mTOR expression of pancreatic cancer BxPC-3 cells at the invasive front in vitro, and promotes tumor growth and invasion in vivo
por: FUJIWARA, MASAYA, et al.
Publicado: (2016)

Analysis of illegitimate genomic integration mediated by zinc-finger nucleases: implications for specificity of targeted gene correction
por: Olsen, Petter A, et al.
Publicado: (2010)

Efficacy Evaluation of Combination Treatment Using Gemcitabine and Radioimmunotherapy with (90)Y-Labeled Fully Human Anti-CD147 Monoclonal Antibody 059-053 in a BxPC-3 Xenograft Mouse Model of Refractory Pancreatic Cancer
por: Sugyo, Aya, et al.
Publicado: (2018)

The Adenoviral E1B-55k Protein Present in HEK293 Cells Mediates Abnormal Accumulation of Key WNT Signaling Proteins in Large Cytoplasmic Aggregates
por: Olsen, Petter Angell, et al.
Publicado: (2021)

PcG-Mediated Higher-Order Chromatin Structures Modulate Replication Programs at the Drosophila BX-C
por: Lo Sardo, Federica, et al.
Publicado: (2013)

Increased benzoxazinoid (Bx) levels in wheat seedlings via jasmonic acid treatment and etiolation and their effects on Bx genes including Bx6
por: Sue, Masayuki, et al.
Publicado: (2021)

Comparison of commercial nanoliquid chromatography columns for fast, targeted mass spectrometry-based proteomics
por: Vehus, Tore, et al.
Publicado: (2016)

Molecular Characterization and Functional Analysis of Three Autophagy Genes, BxATG5, BxATG9, and BxATG16, in Bursaphelenchus xylophilus
por: Liu, Hong-Bin, et al.
Publicado: (2019)

Open Tubular Lab-On-Column/Mass Spectrometry for Targeted Proteomics of Nanogram Sample Amounts
por: Hustoft, Hanne Kolsrud, et al.
Publicado: (2014)

Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models
por: Waaler, Jo, et al.
Publicado: (2020)

DKK3 blocked translocation of β‐catenin/EMT induced by hypoxia and improved gemcitabine therapeutic effect in pancreatic cancer Bxpc‐3 cell
por: Guo, Qingqu, et al.
Publicado: (2015)

Slug-Dependent Upregulation of L1CAM Is Responsible for the Increased Invasion Potential of Pancreatic Cancer Cells following Long-Term 5-FU Treatment
por: Lund, Kaja, et al.
Publicado: (2015)

Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines
por: Mygland, Line, et al.
Publicado: (2021)

Pancreas-on-a-Chip Technology for Transplantation Applications
por: Abadpour, Shadab, et al.
Publicado: (2020)

Classification Class B Subclasss BX : Religion-Christian denominations.
Publicado: (1985)

Cannot write session to /tmp/vufind_sessions/sess_s7hgg7lq2qmko4dm6qeke14qg3