No Evidence for AID/MBD4-Coupled DNA Demethylation in Zebrafish Embryos

The mechanisms responsible for active DNA demethylation remain elusive in Metazoa. A previous study that utilized zebrafish embryos provided a potent mechanism for active demethylation in which three proteins, AID, MBD4, and GADD45 are involved. We recently found age-dependent DNA hypomethylation in...

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Detalles Bibliográficos
Autores principales: Shimoda, Nobuyoshi, Hirose, Kentaro, Kaneto, Reiya, Izawa, Toshiaki, Yokoi, Hayato, Hashimoto, Naohiro, Kikuchi, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275248/
https://www.ncbi.nlm.nih.gov/pubmed/25536520
http://dx.doi.org/10.1371/journal.pone.0114816

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275248/
https://www.ncbi.nlm.nih.gov/pubmed/25536520
http://dx.doi.org/10.1371/journal.pone.0114816

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