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No Evidence for AID/MBD4-Coupled DNA Demethylation in Zebrafish Embryos

The mechanisms responsible for active DNA demethylation remain elusive in Metazoa. A previous study that utilized zebrafish embryos provided a potent mechanism for active demethylation in which three proteins, AID, MBD4, and GADD45 are involved. We recently found age-dependent DNA hypomethylation in...

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Detalles Bibliográficos
Autores principales:	Shimoda, Nobuyoshi, Hirose, Kentaro, Kaneto, Reiya, Izawa, Toshiaki, Yokoi, Hayato, Hashimoto, Naohiro, Kikuchi, Yutaka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275248/ https://www.ncbi.nlm.nih.gov/pubmed/25536520 http://dx.doi.org/10.1371/journal.pone.0114816

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