Matrix Metalloproteinase-3 Causes Dopaminergic Neuronal Death through Nox1-Regenerated Oxidative Stress

In the present study we investigated the interplay between matrix metalloproteinase 3 (MMP3) and NADPH oxidase 1 (Nox1) in the process of dopamine (DA) neuronal death. We found that MMP3 activation causes the induction of Nox1 via mitochondrial reactive oxygen species (ROS) production and subsequent...

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Detalles Bibliográficos
Autores principales: Choi, Dong-Hee, Kim, Ji-Hye, Seo, Joo-Ha, Lee, Jongmin, Choi, Wahn Soo, Kim, Yoon-Seong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275264/
https://www.ncbi.nlm.nih.gov/pubmed/25536219
http://dx.doi.org/10.1371/journal.pone.0115954

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275264/
https://www.ncbi.nlm.nih.gov/pubmed/25536219
http://dx.doi.org/10.1371/journal.pone.0115954

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