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Matrix Metalloproteinase-3 Causes Dopaminergic Neuronal Death through Nox1-Regenerated Oxidative Stress
In the present study we investigated the interplay between matrix metalloproteinase 3 (MMP3) and NADPH oxidase 1 (Nox1) in the process of dopamine (DA) neuronal death. We found that MMP3 activation causes the induction of Nox1 via mitochondrial reactive oxygen species (ROS) production and subsequent...
Autores principales: | Choi, Dong-Hee, Kim, Ji-Hye, Seo, Joo-Ha, Lee, Jongmin, Choi, Wahn Soo, Kim, Yoon-Seong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275264/ https://www.ncbi.nlm.nih.gov/pubmed/25536219 http://dx.doi.org/10.1371/journal.pone.0115954 |
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