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Beta-Catenin Regulated ALDH1A1 is a Target in Ovarian Cancer Spheroids

Cancer cells form three dimensional (3D) multicellular aggregates (or spheroids) under non-adherent culture conditions. In ovarian cancer (OC), spheroids serve as a vehicle for cancer cell dissemination in the peritoneal cavity, protecting cells from environmental stress-induced anoikis. To identify...

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Detalles Bibliográficos
Autores principales: Condello, Salvatore, Morgan, Cynthia A., Nagdas, Sarbajeet, Cao, Liyun, Turek, John, Hurley, Thomas D., Matei, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275429/
https://www.ncbi.nlm.nih.gov/pubmed/24954508
http://dx.doi.org/10.1038/onc.2014.178