Cargando…

Beta-Catenin Regulated ALDH1A1 is a Target in Ovarian Cancer Spheroids

Cancer cells form three dimensional (3D) multicellular aggregates (or spheroids) under non-adherent culture conditions. In ovarian cancer (OC), spheroids serve as a vehicle for cancer cell dissemination in the peritoneal cavity, protecting cells from environmental stress-induced anoikis. To identify...

Descripción completa

Detalles Bibliográficos
Autores principales:	Condello, Salvatore, Morgan, Cynthia A., Nagdas, Sarbajeet, Cao, Liyun, Turek, John, Hurley, Thomas D., Matei, Daniela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275429/ https://www.ncbi.nlm.nih.gov/pubmed/24954508 http://dx.doi.org/10.1038/onc.2014.178

Ejemplares similares

A Novel ALDH1A1 Inhibitor Targets Cells with Stem Cell Characteristics in Ovarian Cancer
por: Nwani, Nkechiyere G., et al.
Publicado: (2019)

The Interplay between Oncogenic Signaling Networks and Mitochondrial Dynamics
por: Nagdas, Sarbajeet, et al.
Publicado: (2017)

Tissue transglutaminase activates integrin-linked kinase and β-catenin in ovarian cancer
por: Condello, Salvatore, et al.
Publicado: (2022)

A Novel ALDH1A1 Inhibitor Blocks Platinum-Induced Senescence and Stemness in Ovarian Cancer
por: Muralikrishnan, Vaishnavi, et al.
Publicado: (2022)

ALDH1 Expression Correlates with Favorable Prognosis in Ovarian Cancers
por: Chang, Bin, et al.
Publicado: (2009)

ALDH1 Bio-activates Nifuroxazide to Eradicate ALDH(High) Melanoma-Initiating Cells
por: Sarvi, Sana, et al.
Publicado: (2018)

A Selective ALDH1A3 Inhibitor Impairs Mesothelioma 3-D Multicellular Spheroid Growth and Neutrophil Recruitment
por: Boumya, Sara, et al.
Publicado: (2023)

Interferon-γ signaling is associated with BRCA1 loss-of-function mutations in high grade serous ovarian cancer
por: Cardenas, Horacio, et al.
Publicado: (2019)

ALDH Expression Characterizes G1-Phase Proliferating Beta Cells during Pregnancy
por: Zhang, Lijuan, et al.
Publicado: (2014)

MicroRNAs overexpressed in ovarian ALDH1-positive cells are associated with chemoresistance
por: Park, Young Tae, et al.
Publicado: (2013)

Correlation of ALDH1 and Notch3 Expression: Clinical implication in Ovarian Carcinomas
por: Kim, Mi Joung, et al.
Publicado: (2017)

Inhibition of Wnt/beta-catenin signaling downregulates expression of aldehyde dehydrogenase isoform 3A1 (ALDH3A1) to reduce resistance against temozolomide in glioblastoma in vitro
por: Suwala, Abigail Kora, et al.
Publicado: (2018)

The hunt for elusive cancer stem cells
por: Condello, Salvatore, et al.
Publicado: (2017)

The Outside-In Journey of Tissue Transglutaminase in Cancer
por: Sima, Livia Elena, et al.
Publicado: (2022)

DDB2 represses ovarian cancer cell dedifferentiation by suppressing ALDH1A1
por: Cui, Tiantian, et al.
Publicado: (2018)

Drp1 Promotes KRas-Driven Metabolic Changes to Drive Pancreatic Tumor Growth
por: Nagdas, Sarbajeet, et al.
Publicado: (2019)

ALDH1A2 Is a Candidate Tumor Suppressor Gene in Ovarian Cancer
por: Choi, Jung-A, et al.
Publicado: (2019)

Selective ALDH3A1 Inhibition by Benzimidazole Analogues Increase Mafosfamide Sensitivity in Cancer Cells
por: Parajuli, Bibek, et al.
Publicado: (2014)

Differential expression of aldehyde dehydrogenase 1a1 (ALDH1) in normal ovary and serous ovarian tumors
por: Penumatsa, Krishna, et al.
Publicado: (2010)

Association of ALDH1A1-NEK-2 axis in cisplatin resistance in ovarian cancer cells
por: Uddin, Md. Hafiz, et al.
Publicado: (2020)

The expression of ALDH1 in cervical carcinoma
por: Yao, Tingting, et al.
Publicado: (2011)

ALDH1A3 in CSCs
por: Sullivan, Kelly E., et al.
Publicado: (2017)

ALDH1-High Ovarian Cancer Stem-Like Cells Can Be Isolated from Serous and Clear Cell Adenocarcinoma Cells, and ALDH1 High Expression Is Associated with Poor Prognosis
por: Kuroda, Takafumi, et al.
Publicado: (2013)

Targeting ALDH1A1 to induce Necroptosis in Nasopharyngeal Carcinoma
por: Wang, Haihua, et al.
Publicado: (2022)

ALDH-Dependent Glycolytic Activation Mediates Stemness and Paclitaxel Resistance in Patient-Derived Spheroid Models of Uterine Endometrial Cancer
por: Mori, Yutaro, et al.
Publicado: (2019)

The expression of aldehyde dehydrogenase 1 (ALDH1) in ovarian carcinomas and its clinicopathological associations: a retrospective study
por: Huang, Ruixia, et al.
Publicado: (2015)

In Ovarian Cancer Multicellular Spheroids, Platelet Releasate Promotes Growth, Expansion of ALDH+ and CD133+ Cancer Stem Cells, and Protection against the Cytotoxic Effects of Cisplatin, Carboplatin and Paclitaxel
por: Casagrande, Naike, et al.
Publicado: (2021)

miR-458b-5p regulates ovarian granulosa cells proliferation through Wnt/β-catenin signaling pathway by targeting catenin beta-1
por: Wang, Wenwen, et al.
Publicado: (2021)

Targeting ALDH1A1 by disulfiram/copper complex inhibits non-small cell lung cancer recurrence driven by ALDH-positive cancer stem cells
por: Liu, Xinwei, et al.
Publicado: (2016)

Global Deletion of ALDH1A1 and ALDH1A2 Genes Does Not Affect Viability but Blocks Spermatogenesis
por: Topping, Traci, et al.
Publicado: (2022)

ALDH1B1 Is Crucial for Colon Tumorigenesis by Modulating Wnt/β-Catenin, Notch and PI3K/Akt Signaling Pathways
por: Singh, Surendra, et al.
Publicado: (2015)

Prunus spinosa Extract Sensitized HCT116 Spheroids to 5-Fluorouracil Toxicity, Inhibiting Autophagy
por: Condello, Maria, et al.
Publicado: (2022)

Evaluation of the correlation of vasculogenic mimicry, ALDH1, KiSS-1, and MACC1 in the prediction of metastasis and prognosis in ovarian carcinoma
por: Yu, Lan, et al.
Publicado: (2017)

Intact LKB1 activity is required for survival of dormant ovarian cancer spheroids
por: Peart, Teresa, et al.
Publicado: (2015)

Anti-Proliferation Effect of Theasaponin E(1) on the ALDH-Positive Ovarian Cancer Stem-Like Cells
por: Jia, Ling-Yan, et al.
Publicado: (2018)

Intracellular Doppler Signatures of Platinum Sensitivity Captured by Biodynamic Profiling in Ovarian Xenografts
por: Merrill, Daniel, et al.
Publicado: (2016)

ALDH(HIGH) Population Is Regulated by the AKT/β-Catenin Pathway in a Cervical Cancer Model
por: Sarabia-Sánchez, Miguel Ángel, et al.
Publicado: (2020)

Targeting cancer stem cells with ALDH1A1-based immunotherapy
por: DeLeo, Albert B.
Publicado: (2012)

Linking ALDH1 and retinoic acid signaling
por: Markham, Nicholas O., et al.
Publicado: (2019)

Detection of ALDH1 activity in rabbit hepatic VX2 tumors and isolation of ALDH1 positive cancer stem cells
por: Gehlot, Prashasnika, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_m10rl20im4p2ovmql329q1d9tk