Experimental Design to Evaluate Directed Adaptive Mutation in Mammalian Cells

BACKGROUND: We describe the experimental design for a methodological approach to determine whether directed adaptive mutation occurs in mammalian cells. Identification of directed adaptive mutation would have profound practical significance for a wide variety of biomedical problems, including diseas...

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Detalles Bibliográficos
Autores principales: Bordonaro, Michael, Chiaro, Christopher R, May, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JMIR Publications Inc. 2014
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275479/
https://www.ncbi.nlm.nih.gov/pubmed/25491410
http://dx.doi.org/10.2196/resprot.3860

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275479/
https://www.ncbi.nlm.nih.gov/pubmed/25491410
http://dx.doi.org/10.2196/resprot.3860

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