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Experimental Design to Evaluate Directed Adaptive Mutation in Mammalian Cells
BACKGROUND: We describe the experimental design for a methodological approach to determine whether directed adaptive mutation occurs in mammalian cells. Identification of directed adaptive mutation would have profound practical significance for a wide variety of biomedical problems, including diseas...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
JMIR Publications Inc.
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275479/ https://www.ncbi.nlm.nih.gov/pubmed/25491410 http://dx.doi.org/10.2196/resprot.3860 |