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SUV39H1/H3K9me3 attenuates sulforaphane-induced apoptotic signaling in PC3 prostate cancer cells

The isothiocyanate sulforaphane is a promising molecule for development as a therapeutic agent for patients with metastatic prostate cancer. Sulforaphane induces apoptosis in advanced prostate cancer cells, slows disease progression in vivo and is well tolerated at pharmacological doses. However, th...

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Detalles Bibliográficos
Autores principales: Watson, G W, Wickramasekara, S, Palomera-Sanchez, Z, Black, C, Maier, C S, Williams, D E, Dashwood, R H, Ho, E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275561/
https://www.ncbi.nlm.nih.gov/pubmed/25486523
http://dx.doi.org/10.1038/oncsis.2014.47