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SUV39H1/H3K9me3 attenuates sulforaphane-induced apoptotic signaling in PC3 prostate cancer cells
The isothiocyanate sulforaphane is a promising molecule for development as a therapeutic agent for patients with metastatic prostate cancer. Sulforaphane induces apoptosis in advanced prostate cancer cells, slows disease progression in vivo and is well tolerated at pharmacological doses. However, th...
Autores principales: | Watson, G W, Wickramasekara, S, Palomera-Sanchez, Z, Black, C, Maier, C S, Williams, D E, Dashwood, R H, Ho, E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275561/ https://www.ncbi.nlm.nih.gov/pubmed/25486523 http://dx.doi.org/10.1038/oncsis.2014.47 |
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