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Inhibition of the NLRP3 inflammasome provides neuroprotection in rats following amygdala kindling-induced status epilepticus

BACKGROUND: NLRP3 inflammasome is proposed to regulate inflammation in several neurological diseases, but its role in epilepsy remains largely unknown. This study aimed to investigate the role of the NLRP3 inflammasome in neuroinflammation, spontaneous recurrent seizures (SRS) and hippocampal neuron...

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Detalles Bibliográficos
Autores principales: Meng, Xiang-Fei, Tan, Lan, Tan, Meng-Shan, Jiang, Teng, Tan, Chen-Chen, Li, Meng-Meng, Wang, Hui-Fu, Yu, Jin-Tai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275944/
https://www.ncbi.nlm.nih.gov/pubmed/25516224
http://dx.doi.org/10.1186/s12974-014-0212-5