Cargando…

Inhibition of the NLRP3 inflammasome provides neuroprotection in rats following amygdala kindling-induced status epilepticus

BACKGROUND: NLRP3 inflammasome is proposed to regulate inflammation in several neurological diseases, but its role in epilepsy remains largely unknown. This study aimed to investigate the role of the NLRP3 inflammasome in neuroinflammation, spontaneous recurrent seizures (SRS) and hippocampal neuron...

Descripción completa

Detalles Bibliográficos
Autores principales:	Meng, Xiang-Fei, Tan, Lan, Tan, Meng-Shan, Jiang, Teng, Tan, Chen-Chen, Li, Meng-Meng, Wang, Hui-Fu, Yu, Jin-Tai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275944/ https://www.ncbi.nlm.nih.gov/pubmed/25516224 http://dx.doi.org/10.1186/s12974-014-0212-5

Ejemplares similares

NLRP1 inflammasome is activated in patients with medial temporal lobe epilepsy and contributes to neuronal pyroptosis in amygdala kindling-induced rat model
por: Tan, Chen-Chen, et al.
Publicado: (2015)

Genome-Wide microRNA Profiling of Rat Hippocampus after Status Epilepticus Induced by Amygdala Stimulation Identifies Modulators of Neuronal Apoptosis
por: Sun, Zhen, et al.
Publicado: (2013)

Sinomenine exerts anticonvulsant profile and neuroprotective activity in pentylenetetrazole kindled rats: involvement of inhibition of NLRP1 inflammasome
por: Gao, Bo, et al.
Publicado: (2018)

Resveratrol is Neuroprotective and Improves Cognition in Pentylenetetrazole-kindling Model of Epilepsy in Rats
por: Meng, X. J., et al.
Publicado: (2014)

Dynamic oxygen changes during status epilepticus and subsequent endogenous kindling
por: Wolff, Marshal D., et al.
Publicado: (2020)

Itaconate Attenuates Neuroinflammation and Exerts Dopamine Neuroprotection in Parkinson’s Disease through Inhibiting NLRP3 Inflammasome
por: Sun, Guoqing, et al.
Publicado: (2022)

Identification of QTLs Involved in the Development of Amygdala Kindling in the Rat
por: Hashimoto, Ryoko, et al.
Publicado: (2013)

Ischemic Preconditioning Provides Neuroprotection by Inhibiting NLRP3 Inflammasome Activation and Cell Pyroptosis
por: Gao, Li, et al.
Publicado: (2023)

Effect of topiramate on interleukin 6 expression in the hippocampus of amygdala-kindled epileptic rats
por: YE, FEI, et al.
Publicado: (2014)

TRPV1 Contributes to the Neuroprotective Effect of Dexmedetomidine in Pilocarpine-Induced Status Epilepticus Juvenile Rats
por: Tan, Xingqin, et al.
Publicado: (2020)

Research Progress of Mitochondrial Mechanism in NLRP3 Inflammasome Activation and Exercise Regulation of NLRP3 Inflammasome
por: Zhang, Tan, et al.
Publicado: (2021)

Anticonvulsant and Neuroprotective Effects of Dexmedetomidine on Pilocarpine-Induced Status Epilepticus in Rats Using a Metabolomics Approach
por: Tan, Xingqin, et al.
Publicado: (2019)

The trigger for pancreatic disease: NLRP3 inflammasome
por: Liu, Tianming, et al.
Publicado: (2023)

The Spatiotemporal Dynamics of Phase Synchronization during Epileptogenesis in Amygdala-Kindling Mice
por: Li, Jia-Jia, et al.
Publicado: (2016)

Interaction between Thalamus and Hippocampus in Termination of Amygdala-Kindled Seizures in Mice
por: Zhang, Zhen, et al.
Publicado: (2016)

NLRP3 Inflammasome in Metabolic-Associated Kidney Diseases: An Update
por: Xiong, Wei, et al.
Publicado: (2021)

The Neuroprotective Effect of Astaxanthin on Pilocarpine-Induced Status Epilepticus in Rats
por: Deng, Xiaolin, et al.
Publicado: (2019)

Neuroprotective effects of deep hypothermia in refractory status epilepticus
por: Niquet, Jerome, et al.
Publicado: (2015)

Efficacy and safety of atypical antipsychotic drug treatment for dementia: a systematic review and meta-analysis
por: Tan, Lin, et al.
Publicado: (2015)

Retraction Note: Efficacy and safety of atypical antipsychotic drug treatment for dementia: a systematic review and meta-analysis
por: Tan, Lin, et al.
Publicado: (2016)

HCV Genomic RNA Activates the NLRP3 Inflammasome in Human Myeloid Cells
por: Chen, Wei, et al.
Publicado: (2014)

Resveratrol as a Therapeutic Agent for Alzheimer's Disease
por: Ma, Teng, et al.
Publicado: (2014)

Methylene Blue Exerts Anticonvulsant and Neuroprotective Effects on Self-Sustaining Status Epilepticus (SSSE) Induced by Prolonged Basolateral Amygdala Stimulation in Wistar Rats
por: Cui, Zhi-qiang, et al.
Publicado: (2018)

The NLRP3 inflammasome: contributions to inflammation-related diseases
por: Chen, Ying, et al.
Publicado: (2023)

The amygdala lesioning due to status epilepticus – Changes in mechanisms controlling chloride homeostasis
por: Santos, Luiz E.C., et al.
Publicado: (2023)

Rapid Amygdala Kindling Causes Motor Seizure and Comorbidity of Anxiety- and Depression-Like Behaviors in Rats
por: Chen, Shang-Der, et al.
Publicado: (2016)

Zinc provides neuroprotection by regulating NLRP3 inflammasome through autophagy and ubiquitination in a spinal contusion injury model
por: Lin, Jia‐quan, et al.
Publicado: (2020)

Oleanolic Acid Provides Neuroprotection against Ischemic Stroke through the Inhibition of Microglial Activation and NLRP3 Inflammasome Activation
por: Sapkota, Arjun, et al.
Publicado: (2022)

NLRP3 inflammasome activation contributes to the cognitive decline after cardiac surgery
por: Ma, Gang, et al.
Publicado: (2022)

Abnormal amygdala subregional-sensorimotor connectivity correlates with positive symptom in schizophrenia
por: Zhang, Meng, et al.
Publicado: (2020)

Matrix Metalloproteinases and Their Multiple Roles in Alzheimer's Disease
por: Wang, Xiang-Xiang, et al.
Publicado: (2014)

Role of the NLRP3 Inflammasome: Insights Into Cancer Hallmarks
por: Lin, Ting-Yi, et al.
Publicado: (2021)

The NLRP3 Inflammasome as a Novel Therapeutic Target for Cardiac Fibrosis
por: Fan, Jiwen, et al.
Publicado: (2022)

The role of NLRP3 inflammasome in 5-fluorouracil resistance of oral squamous cell carcinoma
por: Feng, Xiaodong, et al.
Publicado: (2017)

Predicting the Functional Outcome of Adult Patients with Status Epilepticus
por: Lin, Chih-Hsiang, et al.
Publicado: (2019)

The protective effect of Epimedii Folium and Curculiginis Rhizoma on Alzheimer’s disease by the inhibitions of NF-κB/MAPK pathway and NLRP3 inflammasome
por: Lan, Zhou, et al.
Publicado: (2017)

Inhibition of the NLRP3-inflammasome as a potential approach for neuroprotection after stroke
por: Ismael, Saifudeen, et al.
Publicado: (2018)

Amentoflavone Affects Epileptogenesis and Exerts Neuroprotective Effects by Inhibiting NLRP3 Inflammasome
por: Rong, Shikuo, et al.
Publicado: (2019)

Using Kindle: your guide to all things Kindle and Kindle DX
por: Cheshire, Jim
Publicado: (2011)

NLRP3 inflammasome-induced pyroptosis in digestive system tumors
por: Wen, Jiexia, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_m4nlroh073lq6gunnf1e8101mq