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Constitutively altered frequencies of circulating follicullar helper T cell counterparts and their subsets in rheumatoid arthritis

INTRODUCTION: Circulating CD4 T cells expressing CXCR5, ICOS and/or PD-1 are counterparts of follicular helper T cells (Tfh). There are three subpopulations of circulating Tfh (cTfh): CXCR5 + CXCR3 + CCR6- (Tfh-Th1), CXCR5 + CXCR3-CCR6- (Tfh-Th2) and CXCR5 + CXCR3-CCR6+ (Tfh-Th17). Our objective was...

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Detalles Bibliográficos
Autores principales: Arroyo-Villa, Irene, Bautista-Caro, María-Belén, Balsa, Alejandro, Aguado-Acín, Pilar, Bonilla-Hernán, María-Gema, Plasencia, Chamaida, Villalba, Alejandro, Nuño, Laura, Puig-Kröger, Amaya, Martín-Mola, Emilio, Miranda-Carús, María-Eugenia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275955/
https://www.ncbi.nlm.nih.gov/pubmed/25475240
http://dx.doi.org/10.1186/s13075-014-0500-6