The essential Schizosaccharomyces pombe Pfh1 DNA helicase promotes fork movement past G-quadruplex motifs to prevent DNA damage

BACKGROUND: G-quadruplexes (G4s) are stable non-canonical DNA secondary structures consisting of stacked arrays of four guanines, each held together by Hoogsteen hydrogen bonds. Sequences with the ability to form these structures in vitro, G4 motifs, are found throughout bacterial and eukaryotic gen...

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Detalles Bibliográficos
Autores principales: Sabouri, Nasim, Capra, John A, Zakian, Virginia A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275981/
https://www.ncbi.nlm.nih.gov/pubmed/25471935
http://dx.doi.org/10.1186/s12915-014-0101-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275981/
https://www.ncbi.nlm.nih.gov/pubmed/25471935
http://dx.doi.org/10.1186/s12915-014-0101-5

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