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Leukotriene B4 activates intracellular calcium and augments human osteoclastogenesis

INTRODUCTION: Bone erosion in inflammatory arthritis depends on the recruitment and activation of bone resorbing cells, the osteoclasts. Interleukin-23 (IL-23) has been primarily implicated in mediating inflammatory bone loss via the differentiation of Th17 receptor activator of nuclear factor κB li...

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Detalles Bibliográficos
Autores principales: Dixit, Neha, Wu, Dennis J, Belgacem, Yesser H, Borodinsky, Laura N, Gershwin, M Eric, Adamopoulos, Iannis E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276054/
https://www.ncbi.nlm.nih.gov/pubmed/25443625
http://dx.doi.org/10.1186/s13075-014-0496-y