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Determination of stress-induced degradation products of cetirizine dihydrochloride by a stability-indicating RP-HPLC method

BACKGROUND: A new, simple and accurate stability-indicating reverse phase high performance liquid chromatography method was developed and validated during the early stage of drug development of an oral lyophilizate dosage form of cetirizine dihydrochloride. METHODS: For RP-HPLC analysis it was used...

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Detalles Bibliográficos
Autores principales: Flórez Borges, Paloma, Pérez Lozano, Pilar, García Montoya, Encarna, Miñarro, Montserrat, Ticó, Josep R, Jo, Enric, Suñe Negre, Josep M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276092/
https://www.ncbi.nlm.nih.gov/pubmed/25487685
http://dx.doi.org/10.1186/s40199-014-0082-5