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The interleukin-1 receptor antagonist anakinra improves endothelial dysfunction in streptozotocin-induced diabetic rats

BACKGROUND: Endothelial dysfunction is a crucial early phenomenon in vascular diseases linked to diabetes mellitus and associated to enhanced oxidative stress. There is increasing evidence about the role for pro-inflammatory cytokines, like interleukin-1β (IL-1β), in developing diabetic vasculopathy...

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Detalles Bibliográficos
Autores principales: Vallejo, Susana, Palacios, Erika, Romacho, Tania, Villalobos, Laura, Peiró, Concepción, Sánchez-Ferrer, Carlos F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276125/
https://www.ncbi.nlm.nih.gov/pubmed/25518980
http://dx.doi.org/10.1186/s12933-014-0158-z