Hyperglycemia, p53 and mitochondrial pathway of apoptosis are involved in the susceptibility of diabetic models to ischemic acute kidney injury

Patients with chronic kidney diseases, including diabetic nephropathy, are more susceptible to acute kidney injury (AKI) and have a worse prognosis following AKI. However, the underlying mechanism is unclear. Here we tested whether diabetic mice were more sensitive to AKI and show that renal ischemi...

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Detalles Bibliográficos
Autores principales: Peng, Jianping, Li, Xiaoning, Zhang, Dongshan, Chen, Jian-Kang, Su, Yunchao, Smith, Sylvia B., Dong, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276728/
https://www.ncbi.nlm.nih.gov/pubmed/24963915
http://dx.doi.org/10.1038/ki.2014.226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276728/
https://www.ncbi.nlm.nih.gov/pubmed/24963915
http://dx.doi.org/10.1038/ki.2014.226

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