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Attenuation of Peripheral Regulatory T-Cell Suppression of Skin-Homing CD8(+)T Cells in Atopic Dermatitis
PURPOSE: Cutaneous lymphocyte-associated antigen (CLA)-expressing CD8(+)T cells have been known to play an important role in the pathogenesis of atopic dermatitis (AD). However, the mechanisms underlying the loss of self-tolerance remain unclear. Regulatory T cells (Tregs) play a key role in the dev...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Yonsei University College of Medicine
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276756/ https://www.ncbi.nlm.nih.gov/pubmed/25510765 http://dx.doi.org/10.3349/ymj.2015.56.1.196 |