Attenuation of Peripheral Regulatory T-Cell Suppression of Skin-Homing CD8(+)T Cells in Atopic Dermatitis

PURPOSE: Cutaneous lymphocyte-associated antigen (CLA)-expressing CD8(+)T cells have been known to play an important role in the pathogenesis of atopic dermatitis (AD). However, the mechanisms underlying the loss of self-tolerance remain unclear. Regulatory T cells (Tregs) play a key role in the dev...

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Detalles Bibliográficos
Autores principales: Zhang, Bao-Xiang, Lyu, Jun-Cheng, Liu, Hai-Bo, Feng, Dian-Qin, Zhang, Dian-Cai, Bi, Xing-Jie, Duan, Zhi-Wu, Ding, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276756/
https://www.ncbi.nlm.nih.gov/pubmed/25510765
http://dx.doi.org/10.3349/ymj.2015.56.1.196

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