TAp73 promotes anti-senescence-anabolism not proliferation

TAp73, a member of the p53 family, has been traditionally considered a tumor suppressor gene, but a recent report has claimed that it can promote cellular proliferation. This assumption is based on biochemical evidence of activation of anabolic metabolism, with enhanced pentose phosphate shunt (PPP)...

Descripción completa

Detalles Bibliográficos
Autores principales: Agostini, Massimiliano, Niklison-Chirou, Maria Victoria, Catani, Maria Valeria, Knight, Richard A., Melino, Gerry, Rufini, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276786/
https://www.ncbi.nlm.nih.gov/pubmed/25554796

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276786/
https://www.ncbi.nlm.nih.gov/pubmed/25554796

Ejemplares similares