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TAp73 promotes anti-senescence-anabolism not proliferation
TAp73, a member of the p53 family, has been traditionally considered a tumor suppressor gene, but a recent report has claimed that it can promote cellular proliferation. This assumption is based on biochemical evidence of activation of anabolic metabolism, with enhanced pentose phosphate shunt (PPP)...
Autores principales: | Agostini, Massimiliano, Niklison-Chirou, Maria Victoria, Catani, Maria Valeria, Knight, Richard A., Melino, Gerry, Rufini, Alessandro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276786/ https://www.ncbi.nlm.nih.gov/pubmed/25554796 |
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