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Loss of Nfkb1 leads to early onset aging

NF-(B is a major regulator of age-dependent gene expression and the p50/NF-(B1 subunit is an integral modulator of NF-(B signaling. Here, we examined Nfkb1(−/−) mice to investigate the relationship between this subunit and aging. Although Nfkb1(−/−) mice appear similar to littermates at six months o...

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Detalles Bibliográficos
Autores principales: Bernal, Giovanna M., Wahlstrom, Joshua S., Crawley, Clayton D., Cahill, Kirk E., Pytel, Peter, Liang, Hua, Kang, Shijun, Weichselbaum, Ralph R., Yamini, Bakhtiar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276787/
https://www.ncbi.nlm.nih.gov/pubmed/25553648