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Loss of Nfkb1 leads to early onset aging
NF-(B is a major regulator of age-dependent gene expression and the p50/NF-(B1 subunit is an integral modulator of NF-(B signaling. Here, we examined Nfkb1(−/−) mice to investigate the relationship between this subunit and aging. Although Nfkb1(−/−) mice appear similar to littermates at six months o...
Autores principales: | Bernal, Giovanna M., Wahlstrom, Joshua S., Crawley, Clayton D., Cahill, Kirk E., Pytel, Peter, Liang, Hua, Kang, Shijun, Weichselbaum, Ralph R., Yamini, Bakhtiar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276787/ https://www.ncbi.nlm.nih.gov/pubmed/25553648 |
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