Iron promotes protein insolubility and aging in C. elegans

Many late-onset proteotoxic diseases are accompanied by a disruption in homeostasis of metals (metallostasis) including iron, copper and zinc. Although aging is the most prominent risk factor for these disorders, the impact of aging on metallostasis and its role in proteotoxic disease remain poorly...

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Detalles Bibliográficos
Autores principales: Klang, Ida M., Schilling, Birgit, Sorensen, Dylan J., Sahu, Alexandria K., Kapahi, Pankaj, Andersen, Julie K., Swoboda, Peter, Killilea, David W., Gibson, Bradford W., Lithgow, Gordon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276790/
https://www.ncbi.nlm.nih.gov/pubmed/25554795

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276790/
https://www.ncbi.nlm.nih.gov/pubmed/25554795

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