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Protein Transmission, Seeding and Degradation: Key Steps for α-Synuclein Prion-Like Propagation

Converging lines of evidence suggest that cell-to-cell transmission and the self-propagation of pathogenic amyloidogenic proteins play a central role in the initiation and the progression of several neurodegenerative disorders. This "prion-like" hypothesis has been recently reported for α-...

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Detalles Bibliográficos
Autores principales: Oueslati, Abid, Ximerakis, Methodios, Vekrellis, Kostas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Brain and Neural Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276803/
https://www.ncbi.nlm.nih.gov/pubmed/25548532
http://dx.doi.org/10.5607/en.2014.23.4.324