Alpharetroviral Vectors: From a Cancer-Causing Agent to a Useful Tool for Human Gene Therapy

Gene therapy using integrating retroviral vectors has proven its effectiveness in several clinical trials for the treatment of inherited diseases and cancer. However, vector-mediated adverse events related to insertional mutagenesis were also observed, emphasizing the need for safer therapeutic vect...

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Detalles Bibliográficos
Autores principales: Suerth, Julia D., Labenski, Verena, Schambach, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276931/
https://www.ncbi.nlm.nih.gov/pubmed/25490763
http://dx.doi.org/10.3390/v6124811

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276931/
https://www.ncbi.nlm.nih.gov/pubmed/25490763
http://dx.doi.org/10.3390/v6124811

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