Repositioning of Tyrosine Kinase Inhibitors as Antagonists of ATP-Binding Cassette Transporters in Anticancer Drug Resistance

The phenomenon of multidrug resistance (MDR) has attenuated the efficacy of anticancer drugs and the possibility of successful cancer chemotherapy. ATP-binding cassette (ABC) transporters play an essential role in mediating MDR in cancer cells by increasing efflux of drugs from cancer cells, hence r...

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Detalles Bibliográficos
Autores principales: Wang, Yi-Jun, Zhang, Yun-Kai, Kathawala, Rishil J., Chen, Zhe-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276951/
https://www.ncbi.nlm.nih.gov/pubmed/25268163
http://dx.doi.org/10.3390/cancers6041925

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276951/
https://www.ncbi.nlm.nih.gov/pubmed/25268163
http://dx.doi.org/10.3390/cancers6041925

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