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Morpholino-Mediated Isoform Modulation of Vascular Endothelial Growth Factor Receptor-2 (VEGFR2) Reduces Colon Cancer Xenograft Growth

Angiogenesis plays a key role in tumor growth. Vascular endothelial growth factor (VEGF) is a pro-angiogenic that is involved in tumor angiogenesis. When VEGF binds to membrane-bound vascular endothelial growth factor receptor 2 (mVEGFR2), it promotes angiogenesis. Through alternative polyadenylatio...

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Detalles Bibliográficos
Autores principales: Stagg, Brian C., Uehara, Hironori, Lambert, Nathan, Rai, Ruju, Gupta, Isha, Radmall, Bryce, Bates, Taylor, Ambati, Balamurali K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276969/
https://www.ncbi.nlm.nih.gov/pubmed/25534570
http://dx.doi.org/10.3390/cancers6042330