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Morpholino-Mediated Isoform Modulation of Vascular Endothelial Growth Factor Receptor-2 (VEGFR2) Reduces Colon Cancer Xenograft Growth
Angiogenesis plays a key role in tumor growth. Vascular endothelial growth factor (VEGF) is a pro-angiogenic that is involved in tumor angiogenesis. When VEGF binds to membrane-bound vascular endothelial growth factor receptor 2 (mVEGFR2), it promotes angiogenesis. Through alternative polyadenylatio...
Autores principales: | Stagg, Brian C., Uehara, Hironori, Lambert, Nathan, Rai, Ruju, Gupta, Isha, Radmall, Bryce, Bates, Taylor, Ambati, Balamurali K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276969/ https://www.ncbi.nlm.nih.gov/pubmed/25534570 http://dx.doi.org/10.3390/cancers6042330 |
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