Targeting the integrated networks of aggresome formation, proteasome, and autophagy potentiates ER stress-mediated cell death in multiple myeloma cells

The inhibitory effects of macrolide antibiotics including clarithromycin (CAM) on autophagy flux have been reported. Although a macrolide antibiotic exhibits no cytotoxicity, its combination with bortezomib (BZ), a proteasome inhibitor, for the simultaneous blocking of the ubiquitin (Ub)-proteasome...

Descripción completa

Detalles Bibliográficos
Autores principales: MORIYA, SHOTA, KOMATSU, SEIICHIRO, YAMASAKI, KAHO, KAWAI, YUSUKE, KOKUBA, HIROKO, HIROTA, AYAKO, CHE, XIAO-FANG, INAZU, MASATO, GOTOH, AKIHIKO, HIRAMOTO, MASAKI, MIYAZAWA, KEISUKE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277245/
https://www.ncbi.nlm.nih.gov/pubmed/25422130
http://dx.doi.org/10.3892/ijo.2014.2773

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277245/
https://www.ncbi.nlm.nih.gov/pubmed/25422130
http://dx.doi.org/10.3892/ijo.2014.2773

Ejemplares similares