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Negative Elongation Factor Controls Energy Homeostasis in Cardiomyocytes
Negative elongation factor (NELF) is known to enforce promoter-proximal pausing of RNA polymerase II (Pol II), a pervasive phenomenon observed across multicellular genomes. However, the physiological impact of NELF on tissue homeostasis remains unclear. Here, we show that whole-body conditional dele...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277258/ https://www.ncbi.nlm.nih.gov/pubmed/24656816 http://dx.doi.org/10.1016/j.celrep.2014.02.028 |