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Negative Elongation Factor Controls Energy Homeostasis in Cardiomyocytes

Negative elongation factor (NELF) is known to enforce promoter-proximal pausing of RNA polymerase II (Pol II), a pervasive phenomenon observed across multicellular genomes. However, the physiological impact of NELF on tissue homeostasis remains unclear. Here, we show that whole-body conditional dele...

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Detalles Bibliográficos
Autores principales: Pan, Haihui, Qin, Kunhua, Guo, Zhanyong, Ma, Yonggang, April, Craig, Gao, Xiaoli, Andrews, Thomas G., Bokov, Alex, Zhang, Jianhua, Chen, Yidong, Weintraub, Susan T., Fan, Jian-Bing, Wang, Degeng, Hu, Yanfen, Aune, Gregory J., Lindsey, Merry L., Li, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277258/
https://www.ncbi.nlm.nih.gov/pubmed/24656816
http://dx.doi.org/10.1016/j.celrep.2014.02.028