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Endothelial Protein C Receptor Gene Variants Not Associated with Severe Malaria in Ghanaian Children

BACKGROUND: Two recent reports have identified the Endothelial Protein C Receptor (EPCR) as a key molecule implicated in severe malaria pathology. First, it was shown that EPCR in the human microvasculature mediates sequestration of Plasmodium falciparum-infected erythrocytes. Second, microvascular...

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Detalles Bibliográficos
Autores principales: Schuldt, Kathrin, Ehmen, Christa, Evans, Jennifer, May, Juergen, Ansong, Daniel, Sievertsen, Juergen, Muntau, Birgit, Ruge, Gerd, Agbenyega, Tsiri, Horstmann, Rolf D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277309/
https://www.ncbi.nlm.nih.gov/pubmed/25541704
http://dx.doi.org/10.1371/journal.pone.0115770