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Using common variants to indicate cancer genes

The catalogue of tumour-specific somatic mutations (SMs) is growing rapidly owing to the advent of next-generation sequencing. Identifying those mutations responsible for the development and progression of the disease, so-called driver mutations, will increase our understanding of carcinogenesis and...

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Detalles Bibliográficos
Autores principales: Stead, Lucy F, Thygesen, Helene, Westhead, David R, Rabbitts, Pamela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277321/
https://www.ncbi.nlm.nih.gov/pubmed/24798945
http://dx.doi.org/10.1002/ijc.28951